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Early Signs Of Cystic Fibrosis

Posted on May 10, 2011.
Early Signs Of Cystic FibrosisCystic Fibrosis

Cystic fibrosis is the most common fatal disease and inherited in Caucasian populations, caused by the acquisition of two recessive genes of carriers that are generally not affected themselves. The defect affects the exocrine glands called and most obvious feature is annoying and the development of chronic infections of the respiratory tract. Many organs are affected by glandular abnormalities, but the possible failure of the respiratory system that is the most common cause of death.

The genetic defect affects the thickness of mucus from the body, making it sticky, which in turn makes them more vulnerable to bacterial infection. thick secretions may be present in the airways making them difficult to remove, but they are also present in the pancreas, sweat glands and digestive tract. Initially, the lungs are normal, but shortly after the birth of an infection develops to a certain time and the cycle of infection and inflammation is established with a continuous presence of certain bacteria in the lungs. Gradually the lung membranes thicken and less efficient, ultimately leading to respiratory failure.

The gastrointestinal tract may be obstructed or otherwise affected by thickening the mucus, which reduces the efficiency of absorption of nutrients from food, often an early sign of problems like a baby fails to thrive, ie do not develop as expected. Obstructive adhesions may occur and surgical removal of part of the intestine will be necessary, by further limiting the absorption of nutrients. reducing the effectiveness of pancreatic enzymes occurs and pancreatic insufficiency subsequently develops soluble vitamins such as K, E, D and A are poorly absorbed.

Cystic fibrosis is the place most often a genetic disease whose outcome is fatal, transmitted by a recessive gene that is in nature. The whites of European origin show an incidence of cystic fibrosis of 1 in 3200 live births, while the Asian population at the other end of the scale of 1 to 90,000 were affected. The median age of survival of patients with cystic fibrosis is thirty-seven women who lived for years much less. The lung disease deteriorates inexorably from bronchitis to bronchiectasis and end stage disease in the lungs with heart failure. The variability of the disease is substantial, with differences in the progression, the pattern of disease, severity of symptoms and the age at diagnosis.

Inflammation of the gallbladder and gallstones are higher in people with cystic fibrosis of the typical population. Puberty and the development of secondary sexual characteristics are usually late, infertility in men due to the absence of formation of the vas deferens, while women's fertility can be reduced to some extent. From a social stratum of low socioeconomic status is associated with worse lung disease on. Men are less affected by lung symptoms than females, with females growing more severe lung disease and a younger age at death.

Diagnosis and treatment of cystic fibrosis is a complex issue involving a large number of body systems, so a multidisciplinary team is necessary for a thorough evaluation, preferably in a center that specializes in these conditions. Once the diagnosis and investigations have been supported, the treatment plan involves many aspects of disease management. Patient and / or parent education is crucial that the lifespan and quality of life is strongly affected by patient adherence to treatment. Coping with a chronic disabling and may require advice and technical airway and the use of nebulizers and inhalers should be taught by a physiotherapist.

Management of complications of respiratory disease may require surgical intervention to treat problems of this type by.

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