Posted on February 19, 2010.
How to bypass gastric surgery cure diabetes? Please help?
Im a presentation Monday on the topic of gastric bypass surgery such as Roux-en-Y and the duodenal switch is proved to cure or reverse diabetes. I found some possible explanations Thedrio on how this is possible but I wanted to see if someone could come through with some other items. Any help I would greatly appreciate
Looking at the name of your avatar you could be an MD, so I'm probably not telling you anything by saying there are two types of type 1 diabetes in which insulin production is diminished, and type 2 ("adulthood"), in which the body's response to insulin is reduced. Type 2 is the type associated with obesity, and we know that even modest weight loss can restore sensitivity to insulin.
I am not an MD or a specialist in diabetes, but according to Wikipedia (for what it's worth), some types of gastric bypass surgery have a high success rate in return for type 2 diabetes. Folli et al. Med Clin North Am 91:393-414.
Although it was initially believed that weight loss is the main cause of the effectiveness of gastric bypass surgery, it is now clear that the deletion of the duodenum and other parts gut may be responsible.
Some recent studies and reviews that must be able to help you:
1: Isr Med Assoc J. May 2008, 10 (5) :350-3.
Laparoscopic Roux-en-Y gastric bypass for the treatment of morbid obesity:
experience with 50 patients.
Khalaileh A, Matot I, C Schweiger, L Appelbaum, R Elazary, Keidar A.
Department of General Surgery, Hadassah-Hebrew University Center Medical
Jerusalem, Israel.
BACKGROUND: Roux-en-Y gastric bypass is currently considered the gold standard
surgical option for the treatment of morbid obesity. Open RYGB is associated with
a high risk of complications. Laparoscopic RYGB has been shown to reduce
perioperative morbidity and improve recovery. OBJECTIVES: To review our
experience with laparoscopic RYGB during a period of 19 months. METHODS: Data
were collected prospectively. The study group included all patients who
underwent laparoscopic RYGB for treatment of morbid obesity as the first
Cooperation between February 2006 and July 2007. Reported results included
results of surgery, weight loss and improve the status of co-morbidities, with
followed by a maximum of 19 months. RESULTS: The mean age of the 50 patients was 36.7
years. the average body mass index was 44.7 kg/m2 (range 35-76 kg / m 2), the average
surgery was 171 minutes. There is no conversion to open surgery. The average
of stay was 4 days (2-7 days). Five patients (10%) developed
complication, but none of them has early reoperation and there was no
death. The mean follow-up was 7 months (range 40 days-19 months). The upper
weight loss was 55% and 61% at 6 and 12 months respectively. Diabetes resolved
completely or significantly improved in all five patients with this condition, as
not hypertension in eight patients out of nine. CONCLUSIONS: Laparoscopic RYGB is
possible and safe. The results in terms of weight loss and correction of
co-morbidities are comparable to other studies previously published. But
Surgeons with experience in advance and laparoscopic bariatric
surgery should attempt this procedure.
1: J Am Diet Assoc. 2008 Apr; 108 (4 Suppl 1): S40-4.
Obesity surgery: evidence for diabetes prevention and management.
Cummings S, Apovian CM, Khaodhiar L.
MGH Weight Center, Massachusetts General Hospital, Boston, MA 02114, USA.
Obesity is associated with an increased risk of developing resistance to insulin and
Type 2 diabetes. Development of type 2 diabetes.
